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Extra info for Bio-inorganic Hybrid Nanomaterials - Strategies Syntheses Characterization and Applications
6). Nanocrystalline HAP–collagen nanocomposites synthesized by biomimetic routes show a structure and composition very close to those of natural bone, providing better results in bone regeneration than nanocomposites prepared by conventional methods such as blending or mixing [94,95]. Murugan and Ramakrishna  have also reviewed the use of tissue-engineered nanocomposites, consisting in the isolation of speciﬁc cells by biopsy and their growth on a suitable nanocomposite scaffold, which is subsequently transplanted into the damaged bone site to promote its regeneration.
The use of bio-nanocomposites in DDS, including DNA non-viral vectors in gene therapy, also represents interesting biomedical applications of biohybrids. ) appear attractive for the development of new biocompatible materials with the ability to uptake, carry and deliver molecular drugs in living organisms. By introducing magnetic properties, these bio-nanocomposites can be useful for drug transport to speciﬁc sites in the organs through guidance with external magnetic ﬁelds. Among the new potential applications of bio-nanocomposites, we have highlighted that diverse inorganic components such as clay-based materials, metal nanoparticles and conductive carbon nanotubes can act as active phases in different type of devices, such as electrochemical sensors and biosensors.
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