By Michael J. Yaszemski
Themes comprise biocompatibility and the biomaterial/tissue interface. Discusses bioabsorbable biomaterials for bone fix, nondegradable fabrics in orthopaedics, and supply structures.
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Daculsi G, Weiss P, Bouler JM, Gauthier O, Millot F, Aguado E. Biphasic calcium phosphate/ hydrosoluble polymer composites: a new concept for bone and dental substitution Biomaterials. Bone 1999; 25:59S–61S. 202. Rizzi SC, Heath DJ, Coombes AG, Bock N, Textor M, Downes S. Biodegradable polymer/hydroxyapatite composites: surface analysis and initial attachment of human osteoblasts. J. Biomed. Mater. Res 2001; 55:475–486. 203. Linhart W, Peters F, Lehman W, Schwartz K, Shilling AF, Amling M, Rueger JM, Epple M.
Cells seeded on ceramicpolymer matrices are presented to retain their characteristic morphology and grew in a multilayer fashion . Hydroxyapatite particles in polymer appeared to provide an anchor for the attachment of cells . Apatite crystals, furthermore, kept the pH of the environment within the physiological range. Acid reaction around the implantation site with PLA and PGA implants can be prevented when polymers are used together with apatites . Thus, a strong inflammatory response was seen according to the degradation of the polymer at 24 months even when they are integrated into the composites .
Experimental studies on a new bioactive bone cement: hydroxyapatite composite resin. Biomaterials 1994; 15:156–160. 161. Sarkar MR, Wachter N, Patka P, Kinzl L. First histological observations on the incorporation of a novel calcium phosphate bone substitute material in human cancellous bone. J. Biomed. Mater. Res 2001; 58:329–334. 162. Stelnicki EJ, Ousternout DK. Hydroxyapatite paste used as an onlay implant for supraorbital and malar augmentation. J. Craniofac. Surg 1997; 8:367–372. 163. Ginebra MP, Fernandez E, de Maeyer EA, Verbeeck RM, Boltong MG, Ginebra J, Driessens FC, Planell JA.