Metabolism and Metabolic Studies
Distribution of diet C is tissue particular with early saturation of the mind and adrenal glands following differential oral dose regimens in guinea pigs
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Additional resources for British Journal of Nutrition (Volume 113, Issue 10)
This study complemented other research that found that carriers of the G variant allele (–219G→T) of the APOE gene specifically reduced insulin resistance when fed a diet rich in monounsaturated fatty acids . Another study observed that a saturated fat load was associated with a greater elevation in postprandial triglycerides in the Thr54/Thr54 polymorphism of the FABP2 gene . On the other hand, an interaction between variants in PPARG and ADBR2 genes affecting eating behavior and body composition was found when a hypocaloric diet was prescribed .
11 genes (15 SNPs) Nieters, 2002 [12 ] n–6 PUFA Obesity risk A substantial elevation of obesity risk with increasing intake of n–6 fatty acids in carriers (1 or 2 alleles) of TNFα, leptin and PPARG variants. ADBR2 Martinez, 2003  CHO CHO/fat ratio BMI/ obesity risk Women with a high CHO intake (>49% VET) had greater risk of obesity in Gln27Gln heterozygotes. PPARG Memisoglu, 2003  Total fat MUFA BMI Intake of monounsaturated fat was inversely associated with BMI among 12 Ala variant carriers.
They pointed to differences between the genetic basis of disease in different ethnicities, and suggested that the information gathered should include consideration of behavior. Surprisingly, however, they failed to highlight the potential importance of diet and/or environment. Their 9 recommendations are reproduced in table 1. Celiac disease provides an example where Ng et al.  showed good agreement between direct-to-consumer testing companies. Celiac disease represents a major food intolerance, with a current prevalence rate of approximately 1 per 100 individuals in the population .