By Tania Kaprealian MD, James Rembert MD, Lawrence W. Margolis MD, Sue S. Yom MD (auth.), Eric K. Hansen, Mack Roach (eds.)
Building at the luck of this book's first version, Dr. Eric Hansen and Dr. Mack Roach have up to date, revised, and multiplied the Handbook of Evidence-based Radiation Oncology, a transportable reference that makes use of evidence-based medication because the foundation for functional therapy thoughts and directions. prepared via physique website, concise medical chapters offer easy accessibility to severe details. very important "pearls" of epidemiology, anatomy, pathology, and medical presentation are highlighted. Key aspects of the work-up are indexed, by means of staging and/or possibility class structures. therapy ideas are mentioned according to level, histology, and/or hazard class. short summaries of key trials and stories offer motive for the thoughts. useful directions for radiation thoughts are defined. eventually, problems and follow-up guidance are defined. Updates from the 1st version comprise fresh colour figures and colour contouring mini-atlases for head and neck, gastrointestinal, prostate, and gynecological tumors; redesigned tables for elevated clarity; new chapters on administration of the neck and unknown basic, scientific radiobiology, and pediatric malignancies and benign stipulations; and new appendices together with the yankee university of Radiology guidance for management of IV distinction.
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Additional resources for Handbook of Evidence-Based Radiation Oncology
Accessed on January 12, 2005. Doubrovsky A, de Wilt JH, Scolyer RA, et al. Sentinel node biopsy provides more accurate staging than elective lymph node dissection in patients with cutaneous melanoma. Ann Surg Oncol. 2004;11:829-836. Greene FL. American Joint Committee on Cancer, American Cancer Society. AJCC Cancer Staging Manual. 6th ed. New York: Springer Verlag; 2002. Kirkwood JM, Ibrahim JG, Sondak VK, et al. High- and low-dose alfa-2b in high-risk melanoma: First analysis of intergroup trial E1690/S9111/C9190.
1979) BTSG: pooled three randomized trials. Compared observation vs. WBRT 45 vs. 50 vs. 55 vs. 60 Gy. MS increased with higher doses, 4Æ7Æ9Æ10 month. Walker et al. (1978) BTSG 6901 – phase III: 222 patients (90% GBM, 10% AA) Æ surgery Æ randomized to observation vs. BCNU alone vs. WBRT 50–60 Gy alone vs. WBRT + BCNU. RT was WB to 50 Gy, then boost to 60 Gy. RT ± BCNU improved MS by 3–6 month vs. observation or BCNU alone. Dose and fractionation J J Roa et al. (2004) – phase III: 100 patients with GBM age ³60 and KPS ³50 randomized to 60 Gy/30 fx vs.
Arise from Schwann cells of myelin sheath of peripheral nerves. Sporadic (unilateral, age 40–50 year) or associated with NF 2 (bilateral). Slow growing, well-circumscribed, expansile, displace adjacent nerves. Symptoms: progressive sensorineuronal hearing loss and vestibular deficits. May affect CN VII function. Expansion into cerebellopontine angle may lead to CN V symptoms. Hydrocephalus may occur. Screening: pure tone and speech audiometry (selective loss of speech discrimination common). Thin slice, gadolinium-enhanced MRI through the cerebellopontine angle is the imaging modality of choice.