By C. Hoffmann, J. Rockstroh, B. Kamps
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Extra info for HIV Medicine 2006
Nevertheless, it is unfortunately often used to "prove" the alleged uselessness of HIV tests. e. 4 falsepositive results per 1,000 samples tested). When to test After an infection, it normally takes between three to twelve weeks before the antibodies produced through the immune response of the infected individual become detectable. An HIV test should therefore not be performed too early after a potential risk contact, even though, understandably, concerned patients may be anxious and press for it.
Immunological and virological events during acute HIV-1 infection During acute HIV-1 infection, the virus replicates extensively in the absence of any detectable adaptive immune response, reaching levels of over 100 million copies HIV-1 RNA/ml. It is during this initial cycle of viral replication that important pathogenic processes are thought to occur. These include the seeding of virus to a range of tissue reservoirs and the destruction of CD4+ T-lymphocytes, in particular within the lymphoid tissues of the gut.
75. Richtlinien zur Gewinnung von Blut und Blutbestandteilen und zur Anwendung von Blutprodukten (Hämotherapie). Bundesgesundheitsbl - Gesundheitsforsch – Gesundheitsschutz. Springer-Verlag 2000, 43:555–589. id=183 76. Risk factors for AIDS among Haitians residing in the United States. Evidence of heterosexual transmission. The Collaborative Study Group of AIDS in Haitian-Americans. JAMA 1987, 257: 635-9. id=3795445 77. Rogers AS, Froggatt JW, Townsend T, et al. Investigation of potential HIV transmission to the patients of an HIV-infected surgeon.