By D. M. Yousem M.D. (auth.), Suresh K. Mukherji MD, J. A. Castelijns MD (eds.)
This quantity offers a accomplished evaluation of the present cutting-edge in imaging of the pinnacle and neck. The publication discusses the position of the traditional modalities akin to magnetic resonance imaging and computed tomography in diagnosing and staging head and neck cancers and in comparing the effectiveness of assorted therapy regimens. furthermore, the amount presents broad perception into the position of rising and interesting applied sciences corresponding to positron emission tomography, magnetic resonance spectroscopy, and 3D quantity rendering. those new modalities and methods, during which the authors have wide adventure, promise to steer profoundly the perform of head and neck imaging and should enhance the end result of therapy of ailments of the top and neck within the future.
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Additional resources for Modern Head and Neck Imaging
The total Cho resonance peak is believed to be composed of Cho, phosphocholine, phosphatidylcholine, and glycerophosphocholine. Elevation of this peak is not specific for SCCA and has been demonstrated in several tumors. Increased levels of Cho are thought to be related to increased cellular membrane phospholipid biosynthesis and raised Cho is, therefore, felt to be an active marker for cellular pro- b Magnetic Resonance Spectroscopy of the Extracranial Head and Neck liferation (LEAN et al. 1992; RUIZ-CABELLO and COHEN 1992; NEGENDAK et al.
1996). These findings suggest that the Cho/Cr ratio is a ubiquitous 1H-MRS tumor marker that can be used to clearly identify the presence of a variety of tumors. It should be emphasized that the Cho/Cr ratio is nonspecific and cannot distinguish between tumors; nor can it differentiate between grades of squamous cell carcinoma or metastatic potential. However, this ratio may be used as a spectral tumor marker in an attempt to identify a malignancy or to differentiate recurrent tumor from nonmalignant posttreatment changes in the extracranial head and neck using 1H-MRS.
The 4-year MR control study of the patients with the pleomorphic adenoma showed no recurrent tumor (Fig. 2). MR thermometry enabled on-line display of the hyperthermic effects, seen as progressively decreased signal from spaces surrounding tumor. Criteria for evaluating the success of treatment included clinical data, such as pain or other local symptoms, and pre- and posttherapeutic changes in signal and tumor morphology. We were able to induce coagulative necrosis in all patients (volume range: 3 cm 3 to 25 cm 3 ) and to reduce clinical symptoms in 9 patients.